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MicroRNA-122-5p inhibition improves inflammation and oxidative stress damage in dietary-induced non-alcoholic fatty liver disease through targeting FOXO3

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Five clinical trials (SURPASS 1-5 trials) conducted in patients with T2DM showed that tirzepatide at 5-15 mg per week could reduce body weight (5.4-11.7kg), which was never seen with a single drug (129)

Travelling with injectable medicines requires careful planning to ensure the product remains within its required temperature range throughout the journey

It remains unavailable outside of clinical trials, with FDA approval not expected until late 2026 or early 2027

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