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By meta-analysis of the individual cardiovascular endpoints, significant improvements were established for all of the following: myocardial infarction, stroke, cardiovascular mortality, all-cause mortality and hospitalisation for heart failure

Over the past decade, studies have shown GLP-1 receptor agonists like semaglutide (Ozempic or Wegovy) reduce food seeking, but also alcohol intake, cocaine reward, nicotine self-administration, and relapse-like behavior spanning multiple drug classes

This accelerated titration must be done carefully and only under provider supervision

Epidemiology and pathophysiology of heart failure As one of the most prevalent consequences of CVD and other cardiometabolic conditions such as diabetes and hypertension, HF remains associated with high mortality rates (Bragazzi et al., 2021)
Burns says he asks every new patient with type 2 diabetes: "Has anyone ever told you this is reversible?" He says, Invariably, they say no. But type 2 diabetes can be reversed through diet

The recommended initial dosing of IGlarLixi for patients previously uncontrolled on lixisenatide or on less than 30 IU basal insulin is 15 U (15 U of glargine and 5 mcg of lixisenatide)
