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Novo Nordisk announced that its rebranded and reformulated oral GLP-1 medication, formerly known as Rybelsus, is now available in the U.S

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Among 48,214 reports (57.5% female), common AEs included nausea and weight loss

Mechanistic hypotheses include reduced leptin-driven T-helper (Th)1/Th17 activity, improved adipokine balance, and modulation of gut-thyroid axis pathways

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