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As a generality, increased serotonin tone is thought to decrease food intake and elicit weight loss (28)

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At the DNA level, it tells a different story

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Reductions in HbA 1c and body weight by gender and age Significantly greater reductions in HbA 1c were achieved by subjects treated with semaglutide than by those receiving placebo, and this decrease was consistent for both genders (ETD for semaglutide 0.5 and 1.0 mg vs placebo: 0.65% [95% CI 0.80
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