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Though newer GLP-1 analogs have taken center stage, DPP-4 inhibitors were the first incretin-based therapies that paved the way for todays metabolic revolution

However, weight loss with these drugs also could lower risk for obesity-related cancers

This guide explains safe laxative use, hydration strategies, and how genetic predispositions may influence your bowel response, helping you have a more informed conversation with your healthcare provider

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Here the authors report that D-allulose triggers GLP-1 release in the gut and GLP-1R signaling on vagal afferents, counteracting arrhythmic overeating, obesity and diabetes.