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Beyond genetics, your starting weight, insulin sensitivity, prior diet history, and concurrent medications all modulate the timeline

Although the researchers replicate a clinical trial finding of a reduction in heart attacks and strokes among patients with existing cardiovascular disease and chronic kidney disease and a reduction in moderate alcohol consumption risk, they find no statistically significant decline in broader emergency department visits or in any major diagnostic category

23% of current GLP-1 users say alcohol got less appealing

Getting dosing right for weight loss means aiming for a higher, steady exposure pattern than what most diabetes treatments require

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Another study found that participants regained an average of 11.6% of their body weight within a year after stopping treatment