glp 1 while breastfeeding can you use a GLP1 breastfeeding? #glp1 #semaglutide #zepbound #mounjaro #breastfeeding GLP-1s and Breastfeeding — Bridges

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A basic one-a-day is not always enough

Kara, et al., 'Effects of Retatrutide on Learning and Memory in Streptozotocin-Induced Diabetic Rats', bioRxiv , Jan

Given the pre-existing data on GLP-1 and glucagon, we designed a double-blinded randomised cross-over study, in which we gave volunteers who were overweight short-term intravenous infusions of glucagon (50 ng/kg/min or 14 pmol/kg/min), GLP-1 (0.8 pmol/kg/min), combination of glucagon + GLP-1 at the same doses, or placebo over 45 minutes, and demonstrated that there was a significant increase in resting energy expenditure with glucagon alone which was preserved with the combination of glucagon + GLP-1, whereas GLP-1 did not affect energy expenditure (66)

[7] You can see this benefit play out in two biomarkers: fasting glucose and HbA1c

Already authorised, Lillys tirzepatide targets both GLP-1 and the glucose-dependent insulinotropic polypeptide (GIP) receptor, which has a complementary role in stimulating insulin secretion and reducing appetite