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ABFM Board Certified in Family Medicine, ABPM Board Certified in Public Health, & General Preventive Medicine

Diabetes Complications 25 , 244246 (2011)

Additive mechanisms: central activation of GLP-1R / GIPR hypothalamic satiety circuits, slowed gastric emptying, amplified glucose-dependent insulin secretion, direct adipocyte lipolysis via GCGR, brown thermogenesis via UCP1, and increased hepatic lipid oxidation

In trials, participants on 12 mg weekly lost an average of 24% of body weight over 48 weeks [2]

And what stimulates the neurons to produce GLP-1

PlexusDx requires baseline depression screening and ongoing mood monitoring for all patients, especially those with mental health history