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4 The role of Sirts in PD Sirtuins (Sirts) are proteins that belong to the nicotinamide adenine dinucleotide (NAD + )-dependent deacetylases family (Histone Deacetylase or HDAC)

One possible explanation for this effect is the suppression of pro-inflammatory cytokines such as TNF- and IL-17 [16]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Meloni AR, DeYoung MB, Lowe C, Parkes DG