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A 20 percent LDL reduction from a weight-loss-oriented triple agonist is therefore a genuinely new observation and helps explain why retatrutide is being developed across cardiovascular, metabolic, and weight-related indications rather than as a pure obesity asset

doi: 10.1038/s41574-018-0016-2

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Eric Topol, MD How impactful is a physicians bias holding back use of these medications

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