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Retatrutide In the first phase 3 trial (TRIUMPH-4), participants lost an average of 28.7% of their body weight at 68 weeks on the highest dose (12mg), with the 9mg dose showing 26.4% weight loss

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This is because semaglutide influences your glucagon-like peptide-1 (GLP-1) levels which regulate your mood

Ask your doctor if youre a candidate for one of these medications

Experiencing these effects does not necessarily mean that treatment is unsuitable

Timing with meals: Drink most of your water between meals, not with them