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GLP-1 medications don't directly weaken this sphincter, but delayed gastric emptying means there's simply more volume and pressure sitting in your stomach at bedtime than your body is used to managing

Transdermal patch versions are not part of the evidence base from major clinical trials

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[DOI] [PubMed] [Google Scholar] 148.Heise T, DeVries JH, Urva S, et al

Truth: Semaglutide and Tirzepatide are safe when used as directed

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