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Although most of the studies reported an association between GLP-1 RA and increased residual gastric contents, evidence linking these medications to a statistically significant rise in regurgitation or aspiration events remains highly inconsistent

Even if youre not taking GLP-1s, sagging skin after weight loss is a common concern

So that was a significant acceleration of time. Just as important, Brenner framed that acceleration as a benefit with clear limits

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Lowering of hemoglobin A1C and risk of cardiovascular outcomes and all-cause mortality, a meta-regression analysis