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Hansoh Pharmaceuticals GLP-1/GIP dual agonist HS-20094, targeting overweight or obesity, has also entered Phase II clinical trials

That would mean a 2027 launch

While complete reversal is challenging, early intervention with the right supplements, diet, and exercise program can significantly improve bone density and reduce fracture risk

Patients should also be aware of potential gallbladder-related symptoms after stopping treatment, particularly if they experienced rapid weight loss while on the medication

Clinical studies (in both obesity and type 2 diabetes) consistently show that GLP-1 RA treatment leads to less hunger, increased satiety, and spontaneous decreases in daily caloric consumption (Zheng et al., 2024)