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Conclusions Small molecule GLP-1 receptor agonists represent an innovative advancement in the management of T2DM and obesity

Obesity 30 , 802840 (2022)

doi: 10.1073/pnas.1219451110 72 WangLLiPTangZYanXFengB

They found other small peptides that control insulin and appetite by acting on two or even three metabolic switches instead of just one

The GLP-1R is expressed in many tissues, including the heart, brain, kidney, liver and immune system