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Other options include SGLT2 inhibitors such as dapagliflozin or empagliflozin, DPP-4 inhibitors like sitagliptin, or traditional agents such as metformin (if not already prescribed), sulfonylureas, or insulin therapy

Apr 2022;26(2):e281-e288

At the 104-week mark, 67.8% of semaglutide users achieved at least 5% weight loss, a clinically meaningful threshold

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Start Low and Increase Dosage Gradually The most effective strategy for preventing severe diarrhea is following a structured dose escalation schedule rather than jumping to therapeutic doses immediately

10.1006/bbrc.1995.1287 6 DeFronzoR