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doi: 10.1111/obr.13296

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Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial

Peptide manufacturing typically scales gradually throughout development: For many historical peptide drugs, that final step remained manageable within existing manufacturing infrastructure