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Efficacy and safety of once-weekly semaglutide 1.0mg vs once-daily liraglutide 1.2mg as add-on to 1-3 oral antidiabetic drugs in subjects with type 2 diabetes (sustain 10)

62,63 Intestinal FXR mediates suppression of lipid absorption, while hepatic FXR inhibits lipid synthesis

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Increases in the percentage of T(/)MCA, (T/G)UDCA, and (T)HDCA were also observed in either the ileum or the feces of MMI + T3-5d mice compared to MMI mice (Fig

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The study also revealed an additional, unexpected benefit: Participants who smoked cigarettes also cut back on their tobacco use during the trial