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doi:10.3389/fendo.2024.1402583

The chart below from Weight regain and cardiometabolic effects after withdrawal of semaglutide also show a rapid regain after stopping the drugs

Page MJ, McKenzie JE, Bossuyt PM et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Common Side Effects Gastrointestinal effects: Nausea, stomach upset, and related GI symptoms are the most common

David Dodick, Atrias Chief Science & Medical Officer

Taking a dose one day early may slightly increase gastrointestinal side effects such as nausea but is generally well tolerated
