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GLP-1 receptor agonists are emerging as a potential first step towards a true multi-hormone approach, and one key theme runs through the conversation: it may be time for type 1 diabetes care to move beyond insulin alone

But pharma is taking back the wheel: Novo launched cash-pay Wegovy via NovoCare at $499/month then ended a partnership with Hims over continued off-label compounding (source) Lilly is offering Zepbound via LillyDirect while suing DTC platforms in CA (source) Hims is hedging with a ZAVA acquisition to expand GLP-1 sales in the EU (source) Most commentary stops at the what. I wanted to understand why

I discuss the issue of weight loss variability in response to the compounds along with how the GLP-1s interact with lifestyle changes

ARFI, Acoustic Radiation Force Impulse

It became increasingly sought because clinical tests and real-world results showed remarkable weight-lowering gains

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