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If the drug is shown to have anti-addiction properties in humans, whether these effects can be maintained after someone stops taking it is also an open question

In some cases, the skin manifestations can serve as a warning sign, prompting individuals to seek medical attention before more severe symptoms develop

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This effect is more clear in animal studies, where weight-matched controls are easy to achieve by restricting access to food and any changes in diet are controlled for

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Obesity development in PWS is driven by dysfunction in neural pathways involved in satiety and reward, dysregulation in hormones regulating satiety and food intake, altered body composition and reduced energy expenditure, as well as the presence of various hormone deficiencies