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10.1111/dom.14166 [DOI] [PubMed] [Google Scholar] 20.Wharton S, Davies M, Dicker D, Lingvay I, Mosenzon O, Rubino DM, Pedersen SD (2022) Managing the gastrointestinal side effects of GLP-1 receptor agonists in obesity: recommendations for clinical practice

The exploration of these neuroprotective qualities underscores the multifaceted benefits of GLP-1 agonists beyond their metabolic effects, positioning them as promising adjunctive therapies in the management of bipolar disorder

If you are on a compounded version, the right move is a conversation with a clinician about transitioning to an FDA-approved product not a cold-stop

For constipation, osmotic or stimulant laxatives may be used when dietary measures are insufficient, whereas loperamide or probiotic supplementation may be considered for persistent diarrhea

Blood Pressure and Lipids Both medications produce similar improvements in cardiovascular risk factors: Blood pressure: Both typically reduce systolic BP by 3-6 mmHg Effects are similar between medications Lipids: Both reduce triglycerides Modest effects on LDL cholesterol Similar lipid improvements Metabolic Comparison Cost and Insurance Cost considerations may influence medication choice for some patients

+ T cell experiment, for which a few similar studies have shown the same result, can be further explored by using additional markers to distinguish the smaller groups of T cells and observe their apoptosis ratio (Sha et al., 2024)