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However, neither GLP-1 nor GLP-2 were active on insulin secretion, but a truncated version of GLP-1 was subsequently found to enhance insulin secretion in various experimental models and human studies (8890)

10 In SUSTAIN FORTE, treatment with semaglutide 2 mg versus 1 mg at week 40 showed superior reduction in HbA1c and additional body weight loss in patients with T2D and elevated glycaemic levels (HbA1c 8%10%) on background metformin with or without a sulphonylurea

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