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Given the results of the SURMOUNT-1 trial on weight loss, the introduction of tirzepatide in possible drug therapies against obesity not associated with diabetes is desirable
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Similarly, while murine studies initially raised concerns about thyroid C-cell tumors, 71 current human data do not suggest an increased risk
JAMA Cardiol (2017) 2(9):10259
Cardiovasc Diabetol 21:169
Mathur et al., Insight into Structure Activity Relationship of DPP-4 Inhibitors for Development of Antidiabetic Agents, Molecules, vol
