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A clinically significant interaction exists between tirzepatide and oral contraceptives, with FDA labeling advising use of non-oral or backup contraception for 4 weeks after initiation and each dose increase
In SURMOUNT-1 (72 weeks), tirzepatide produced mean reductions of 15%, 19.5% and 20.9% at the 5, 10 and 15 mg doses versus 3.1% on placebo, and 90.9% of the 15 mg group lost at least 5% of starting weight

PlexusDx compounded semaglutide at $149 per month represents an 8090% savings for patients with consistent dosing needs

Youll know whether you tolerate these medications well, how much appetite suppression you experience, and what kind of weight loss pace to expect

The insurer will expand the rebate-free model to clients of its pharmacy benefits business starting in 2028
