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We further tested TRPV1 channel modulation via Ca 2+ imaging (Fig

Participants were randomly assigned to one of five therapies: exenatide alone, dapagliflozin alone, dual therapy of exenatide and dapagliflozin, combined dapagliflozin and metformin therapy, or the weight-loss medication phentermine/topiramate extended-release

Whether administered via a needle or swallowed as a tablet, the underlying biological mechanism remains focused on helping you eat less while following a reduced-calorie diet

Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic beta-cells

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10.1016/j.phrs.2019.104611 Pharmacol