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Dapagliflozin, liraglutide, and their combination attenuate diabetes mellitus-associated hepato-renal injuryinsight into oxidative injury/inflammation/apoptosis modulation

doi: 10.1056/NEJMoa1901118 44 GersteinHCSattarNRosenstockJRamasundarahettigeCPratleyRLopesRDet al

The condition encompasses a spectrum of pathophysiologic processes ranging from absolute insulin deficiency (Type 1) to progressive insulin secretory failure superimposed on insulin resistance (Type 2)

The therapeutic window for early failure is narrow (2448 h), whereas intervention for late failure may last several days to weeks

The price of the drug may have increased beyond what the insurance company is willing to pay

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Cianci A., et al