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In a prespecified analysis of the FLOW trial, the use of an SGLT2 inhibitor did not impact the overall benefits of semaglutide on kidney and cardiovascular outcomes in participants with type 2 diabetes and chronic kidney disease.
Semaglutide (SEMA), a GLP1 receptor agonist, effectively reduces body weight
Conclusions Semaglutide plays a positive role in alleviating -cell dysfunction by regulating gut microbiota, and METTL3/14, PDX-1, insulin signal pathway-related genes may be associated with CR.
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