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Description
This is a distinguishing factor from the traditional, secretagogue class of drugs used in the treatment of Type 2 DM, which are not glucose-dependent and therefore carry a risk of hypoglycemia
Tschen SI, Georgia S, Dhawan S, and Bhushan A

Higgins J, Altman DG, Gotzsche PC, et al

Compared to placebo, significant weight reductions were observed with GLP-1 RAs/metformin (WMD: 6.65

Broader Indication Development Pemvidutide Expanding into alcohol use disorder (RECLAIM Phase 2 trial) alongside obesity and MASH, potentially addressing a broader range of metabolic and liver conditions

Advise females not to breastfeed during treatment with RYBELSUS [see Use in Specific Populations (8.2)]
