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Hormonal Changes Alongside changes in metabolism, weight loss can trigger hormonal adjustments that can impact appetite and satiety

These factors preclude generalisation of the results of studies to date

Clinical trials indicate that participants with a BMI 30 kg/m or those with overweight and comorbid conditions such as type 2 diabetes or metabolic-associated fatty liver disease (MASLD) may experience the most pronounced benefits

The intersection of hyperthyroidism and obesity creates a clinical scenario where standard weight loss interventions may backfire

What FDA Approval Will Mean for Retatrutide Assuming retatrutide gets FDA approval (and based on Phase 2 data, that's very likely), several things change: 1