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The most recent developments regarding therapies based on incretin hormones (glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)) are likely to fundamentally change our therapy for type 2 diabetes mellitus (T2DM), obesity and conditions associated with diabetes and obesity, i

Theres clearly a strong link between metabolic and mental health, but framing this like GLP-1s are acting as antidepressants is a stretch

10.1152/ajpendo.00576.2007 112

Ozempic is a brand name for semaglutide, which is a GLP-1 receptor agonist originally developed to treat type 2 diabetes

This model reflects evidence-based practice: initial low doses maximize tolerability, while dose escalation follows clinical response, not insurance thresholds