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The researchers matched adults starting treatment with GLP-1 receptor agonists 1:1 with those initiating DPP-4 inhibitors based on age, sex, race, hemoglobin A1c levels, BMI, underlying comorbidities, commonly used medications, and diabetes therapy

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The New England Journal of Medicine, 385 (6), 503515

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Heres why doctors worry about these medications during pregnancy: Limited Human Research We dont have enough studies on pregnant women taking these drugs

Central Nervous System Effects and Pain Processing GLP-1 receptors in the brain influence appetite, reward, mood, and stress responses