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Certain observational studies and post-market safety reviews have examined a potential association between GLP-1 medications and non-arteritic anterior ischemic optic neuropathy, commonly referred to as NAION

2022 Apr 5;15:10231030

Another approach is to prescribe metronidazole (Flagyl, generic) for the anaerobes along with ciprofloxacin (Cipro, generic) or trimethoprim-sulfamethoxazole (Bactrim, generic) for the aerobes

For those with IR, metformin can be prioritized as foundational metabolic management

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Albiglutide is a long-acting GLP-1RA