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Description
In both patient populations with pre-existing cardiovascular disease, DPP-4 inhibitors are recommended as one possible third-line therapy besides SGLT-2 inhibitors, thiazolidinediones, or insulin, when therapeutic goals are not met with the previous dual combination

Its production cost and price are also key to determining whether the drug can be used by American insurers and the European health care system

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Body mass index (BMI) and previous attempts at weight management