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The Medicines and Healthcare products Regulatory Agency (MHRA) has warned healthcare professionals to be aware of the potential risk of pulmonary aspiration in patients using glucagon-like peptide-1 (GLP-1) or dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (GLP-1 RAs), who undergo surgery or procedures with general anaesthesia or deep sedation

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Liraglutide (3.0 mg, daily subcutaneous injection, n=22) or semaglutide (1.0 mg, weekly subcutaneous injection, n=18) was started 74.5 (51.0, 108.3) months after surgery following a weight regain of 14.7 (10.3, 19.6)%

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GLP-1 receptor agonists stimulate the release of insulin, reduce glucagon secretion, and slow down gastric emptying

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Stanford Medicine clinicians explain why they have safety concerns, and what to do if you are taking one.

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SGLT-2 inhibitors are superior to GLP-1RA in reducing the risk of HHF and renal events

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