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Sugary cocktails and beer add unnecessary calories and can spike blood sugar

Rosenstock J, Frias J, Jastreboff A, et al

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GLP-1 receptor agonists, as a drug class, have been in clinical use since 2005, and semaglutide has been licensed since 2017

Thus, incubating human and rodent islets under high glucose conditions results in increased expression of PC1/3 and increased secretion of GLP-1 (101, 108110), while exposure of -cells to the proinflammatory cytokine, interleukin-6, also increased GLP-1 secretion (112)

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