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retatrutide phase 2 trial obesity nejm 2023 triple agonist π A triple-action once-weekly injection can significantly lower blood sugar and body weight in people with type diabetes, a new 3 shows. is part of an emerging generation π¨Breaking: Retatrutide's first Phase 3
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PGC1a, peroxisome proliferator-activated receptor c coactivator 1a

[15] However, subsequent analysis revealed important context: the increased risk was predominantly observed in patients with pre-existing diabetic retinopathy and those who experienced rapid improvements in glycaemic control

It is important to separate the class mechanism from labeled indication
