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Evidence for Cardiovascular Safety The DPP-4 inhibitors have not demonstrated any sustained or clinically significant reduction in other cardiovascular risk factors, such as blood pressure or lipids

Am J Obstet Gynecol (1995) 173(3 Pt 1):7607

There is no definite upper age limit for GLP-1 use

The STEP trial program, which included over 15,000 participants, demonstrated that semaglutide produces average weight loss of 15-17% of body weight when combined with lifestyle modifications
