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In addition, compared with the non-GLP-1RA group, the researchers reported a substantially lower incidence of knee surgery among those who received the treatment 5.9% vs 1.7% ( P = .014)

10.1016/j.addr.2018.07.009 93 ZhangH.WuT.WuY.PengY.WeiX.LuT.et al (2024)

The side effects are pretty similar to those of injections of the drug, and they can include nausea, diarrhea and vomiting

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Studies in which histamine synthesis was chemically inactivated failed to observe the normal leptin-induced suppression of food intake and decrease in body weight (79, 80, 133)