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These patients receive a signal which tells them not only to eat more, but also to store more of what they eat. When semaglutide binds to the brains GLP-1 receptors, it blocks the AGRP pathway and stimulates the POMC pathway

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Shatha notes an emerging trend among patients seeking GLP-1 agonists for purposes beyond traditional weight management
Feb 13, 2026 Conflicting information everywhere

the drug is pregnancy category C, and barrier contraception is recommended during treatment and for 2 months after discontinuation

Diabetes Canada 2018 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada: Nutrition therapy
