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Last reviewed: May 22, 2026 Last updated: May 22, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Fiber-rich GLP-1 foods, adequate protein, gut microbiome support, circadian rhythm alignment, and targeted nutrients such as berberine all contribute to how to boost GLP-1 without medication

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In the overweight/obese reference group, the use of insulin was reported for the treatment of gestational diabetes in two cases (1%)

A bit of history: It was one of the first GLP-1 drugs ever approved and laid the foundation for everything that came after

Patients interested in accessing retatrutide should speak with their GP or a specialist obesity medicine physician about eligibility for ongoing clinical trials