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Studies tell us that anti-inflammatory foods , an emphasis on whole grains , drinking more water , and replenishing lost electrolytes are key
The degree of systolic blood pressure (SBP) reduction varies across studies

Dual agonists target both the GLP-1R and another specific receptor, such as GIP (glucose-dependent insulinotropic polypeptide) or IGF (insulin-like growth factor) receptors

[DOI] [PubMed] [Google Scholar] 145.Ligumsky H., et al

In the SUSTAIN-6 trial, injectable semaglutide demonstrated a notable effect in reducing the incidence of nonfatal stroke (hazard ratio [HR] 0.61

These generally improve as the body adjusts or when the dose is increased gradually
