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Rssner S, Sjostrom L, Noack R, Meinders AE, Noseda G

Small-molecule drugs are subject to Abbreviated New Drug Application (ANDA) pathways for generic approval, which require demonstration of bioequivalence but not repeat clinical trials

When this communication pathway is disrupted, gut motility tends to worsen and digestive symptoms intensify

Endogenous Glucagon-Like Peptide-1 receptor and Glucose-Dependent insulinotropic polypeptide receptor signaling inhibits Aeroallergen-Induced innate airway inflammation

Patients with type 2 diabetes, especially those with cardiovascular disease, chronic kidney disease, obesity, or NAFLD, may benefit from GLP-1 receptor agonists as part of their treatment regimen

(2009) Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily