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Hepatic function plays a minimal role in GLP-1 elimination, as these medications are primarily degraded by proteolytic enzymes throughout the body rather than hepatic metabolism

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While GLP-1 medications are highly effective, other evidence-based approaches include cognitive-behavioral therapy, mindfulness interventions, optimizing sleep quality, stress management, and dietary strategies that emphasize protein, fiber, and minimally processed foods

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Malnutrition and Dehydration: In extreme cases, the cumulative impact of reduced food intake, frequent vomiting, and the bodys inability to absorb nutrients effectively can result in malnutrition