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Highlights of Prescribing Information: Contrave (naltrexone- hydrochloride and bupropion hydrochloride) extended-release tablets, for oral use

So far, research trials havent prompted regulatory agencies to approve these substances or convinced companies to invest in further development

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For people using the medication as part of a weight management plan, reduced potency can lead to slower progress or stalled weight loss

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Metformin could potentially increase the GLP-1 concentration by increasing its secretion from L cells, and/or by reducing its breakdown by DPP4