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In addition to its intrinsic role in catalysing glycolysis, PFKFB3 was recently reported to be involved in NLRP3 inflammasome-mediated inflammation, oxidative stress, and pyroptosis during sepsis [52]

Jessica Crandall Snyder, a registered dietitian and medical advisor, warns that these drugs "may also impact thermoregulation, making it harder for the body to cool itself effectively