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In the SURMOUNT-1 clinical trial, patients on the highest dose of tirzepatide lost an average of 22.5% of their body weight over 72 weeks the highest average weight loss ever recorded in a Phase 3 obesity trial

Short-term SSRI use induces weight loss seemingly due to temporary appetite suppression and gastrointestinal serotonergic effects

But it was never really the mornings that were my problem