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This uncertainty can delay wider adoption and reimbursement approvals, especially for off-label or preventive use

95% CI, 0.92-1.88) or an SGLT2 inhibitor (HR = 1.16

There are also side effects to taking GLP-1s, most of which are related to gastrointestinal issues

Related Content Metabolic dysfunction-associated steatohepatitis (MASH) remains a significant global health challenge, driven by a complex interplay of lipid dysregulation, inflammation, and

Regarding co-agonist treatment, tirzepatide was recently shown in a post hoc analysis of the SURMOUNT-1 trial to also reduce UACR in overweight/obese people without T2D (88), and similar benefits for kidney function were shown in subjects with heart failure (89)

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