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In SUSTAIN-6, semaglutide treatment reduced the risk of MACE by 26% in a short follow-up duration (median 2.1 years)

Adipose tissue produces estrogen through aromatase conversion

Methods Adults with T2D treated with 2 glucose-lowering agents who initiated GLP-1 RAs or basal insulin from 2010 to 2019 were propensity-score matched (1:1) and followed until October 2021 (intention-to-treat [ITT])

This is educational content about an experimental drug

What is thought to be happening is that there's a combination effect

Side Effects, Risks and Considerations While these medications are effective, there are some additional factors to consider prior to commencing treatment