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GLP-1 medications may help address menopause-related weight gain by regulating appetite and metabolism, but individual response depends on hormonal status, metabolic biomarkers, and genetic predispositions

Did you know that the global rate of obesity has more than doubled since 1990, and adolescent obesity has quadrupled

Gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal pain are among the most frequently reported side effects, especially at the start of treatment

GLP-1 agonists like semaglutide and tirzepatide are groundbreaking for weight loss

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However, heterogeneity in weight loss response, cost, side effects, and need for injections may limit their use in many pediatric patients